Six-month cultured cerebral organoids from human ES cells contain matured neural cells

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Six-month cultured cerebral organoids from human ES cells contain matured neural cells

Recently, researchers have developed protocols for human cerebral organoids using human pluripotent stem cells, which mimic the structure of the developing human brain. Existing research demonstrated that human cerebral organoids which undergo short cultivation periods, contain astrocytes, neurons, and neural stem cells, but lacked mature oligodendrocytes, and mature, fully functional neurons. ...

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ژورنال

عنوان ژورنال: Neuroscience Letters

سال: 2018

ISSN: 0304-3940

DOI: 10.1016/j.neulet.2018.01.040